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Strength Through Pathogenesis
and Pathophysiology of Depression

by Reigh Simuzoshya


Scientists have been searching for more evidence with regard to pathogenesis and pathophysiology of depression and the resultant neurobiological effects thereof. But the elucidation of the underlying pathophysiology of this condition continues to be elusive. Some theories claim that depression is linked to a dysfunction of the dopaminergic and GABA-ergic system. Others assert that it is associated with a deficit of norepinephrine and serotonin exacerbated by an alteration in the expression of neuropeptides. Yet another theory claims that the overdrive of the hypothalamic-pituitary adrenal system is another risk factor for depression.

Chances are that a combination of all these factors can certainly intensify the onset of depression.

Grace by Nathan Furr free photo #12440Depression can be draining. It can take away your energy, dampen your hopes for the future and your drive. It even cripples the desire to do what is needed to feel better. Scientists tell us that some of the symptoms of depression include agitation, significant low sex drive, being irritable, having digestive disorders, experiencing headaches, being fatigued, having feelings of guilty and helplessness as well as insomnia. But there are also times when depressed people might want to sleep all the time.

Although the word ‘depression’ does not appear in the Bible except in the New Living Translation, there are many people who manifested depressive symptoms in the Bible such as Elijah, Hannah, King Saul, John the Baptist, Jeremiah, Job and many others. God does not get upset, nor does He punish us just because we experience discouragement and depression. These disorders are often triggered by events beyond our control such as the death of a loved one, divorce or loss of job.

Living in a fallen, sinful world means that we will experience the tragic dimensions of life from time to time until the Lord comes to take us home.

The joy of our salvation is in the confident assurance of God’s manward abundant mercies and in the realization that He responds to our hurts as a loving Father. The Bible says in Psalm 34:18 that the LORD is close to the brokenhearted and saves those who are crushed in spirit. It also says “And I will pray the Father, and he shall give you another Comforter, that he may abide with you forever,” (John 14:16). Furthermore, knowing that Jesus was a man of sorrows and acquainted with grief (Isaiah 53: 3) means that He is not a stranger to our suffering, and because He has already been there and has overcome, we also can overcome through Him. This is our hope and our strength through it all.

Discover time-tested guidelines for disease prevention that will change your life for good at:  The Perfect Prescription by Reigh Simuzoshya.


The Perfect Prescription
Godly Wisdom on Public Health
by Reigh Simuzoshya

  • Paperback: 436 pages
  • Publisher: Tate Publishing (December 10, 2013)
  • Language: English
  • ISBN-10: 1628548312
  • ISBN-13: 978-1628548310

This book is also available for purchase as an eBook download.

Do you know that God is more interested in your health than you could ever be?

The Bible is full of holistic principles and guidelines, which, if applied consistently, can prevent disease and promote optimum health. Preventive measures are often less costly than curative therapies, and these principles can be applied at individual, family, and community levels.

The human body is a fearful and wonderful machine, capable of performing incredible functions. God has stamped his own image on it. How absurd it is then to look elsewhere other than to the omnipotent and omniscient Manufacturer of the human body for guidelines regarding its well-being and health?

Far from being an obsolete and archaic document saturated with myths and superstition, the Bible is a rich repository, an inexhaustible mine, of counsel for all facets of life, including health and longevity.

Explore the time-tested, efficacious principles that are foundational for disease prevention, health enhancement, and long life straight from the creator of our bodies himself with “The Perfect Prescription.”


see also:

Your Circadian Rhythm and Health

Forgiveness – The Perfect Prescription for Peace of Mind

Science Concurs: Your Faith is Your Perfect Prescription

Elder Abuse – book excerpt


Thanks for visiting.

New post Eric


The Perfect Prescription


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